RATE (Restrictor Analysis Tool for Epitopes)
About the tool:
RATE (Restrictor Analysis Tool for Epitopes) is an automated method that can infer HLA restriction for a set of given epitopes from large datasets of T cell responses in HLA typed subjects. The tool takes two data files, one containing the alleles expressed by the subjects and the other containing the response of the peptides in the subjects. The tool calculates the odds ratio and estimates its significance using Fisher's exact test. It also calculates a parameter called relative frequency similar to odds ratio. The tool was developed with a focus on class II alleles but can also be applied to class I alleles.
The previous version of the tool is available here: RATE version-1